載入...

Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations

Drug-induced readthrough over premature stop codons (PTCs) is a potentially attractive therapy for genetic disorders, but a wide outcome variability has been observed. Through expression studies, we investigated the responsiveness to the readthrough-inducing drug geneticin of 11 rationally selected...

全面介紹

Na minha lista:
書目詳細資料
發表在:Blood
Main Authors: Branchini, Alessio, Ferrarese, Mattia, Campioni, Matteo, Castaman, Giancarlo, Mari, Rosella, Bernardi, Francesco, Pinotti, Mirko
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408560/
https://ncbi.nlm.nih.gov/pubmed/28196793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-738641
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!