Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

BACKGROUND: The Nicoya Peninsula in Costa Rica has one of the highest old-age life expectancies in the world, but the underlying biological mechanisms of this longevity are not well understood. As DNA methylation is hypothesized to be a component of biological aging, we focused on this malleable epi...

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Dettagli Bibliografici
Pubblicato in:Epigenetics Chromatin
Autori principali: McEwen, Lisa M., Morin, Alexander M., Edgar, Rachel D., MacIsaac, Julia L., Jones, Meaghan J., Dow, William H., Rosero-Bixby, Luis, Kobor, Michael S., Rehkopf, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408416/
https://ncbi.nlm.nih.gov/pubmed/28465725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0128-2
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