Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study

BACKGROUND: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown. METHODS: As part of a prospective observational study, enrolment...

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Vydáno v:BMC Infect Dis
Hlavní autoři: Plewes, Katherine, Kingston, Hugh W.F., Ghose, Aniruddha, Maude, Richard J., Herdman, M. Trent, Leopold, Stije J., Ishioka, Haruhiko, Hasan, Md. Mahtab Uddin, Haider, Md. Shafiul, Alam, Shamsul, Piera, Kim A., Charunwatthana, Prakaykaew, Silamut, Kamolrat, Yeo, Tsin W., Faiz, Md. Abul, Lee, Sue J, Mukaka, Mavuto, Turner, Gareth D.H., Anstey, Nicholas M., Jackson Roberts, L., White, Nicholas J., Day, Nicholas P.J., Hossain, Md. Amir, Dondorp, Arjen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408414/
https://ncbi.nlm.nih.gov/pubmed/28449641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2373-1
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