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A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use

BACKGROUND: It has become increasingly apparent that the trophectoderm (TE) at blastocyst stage is much more mosaic than has been appreciated. Whether preimplantation genetic screening (PGS), utilizing a single TE biopsy (TEB), can reliably determine embryo ploidy has, therefore, increasingly been q...

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Pubblicato in:Reprod Biol Endocrinol
Autori principali: Gleicher, Norbert, Metzger, Jacob, Croft, Gist, Kushnir, Vitaly A., Albertini, David F., Barad, David H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408377/
https://ncbi.nlm.nih.gov/pubmed/28449669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-017-0251-8
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