DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection

Sal-like protein 4 (SALL4), an embryonic stem cell transcriptional regulator, is re-expressed by an unknown mechanism in poor prognosis hepatocellular carcinoma (HCC), often associated with chronic hepatitis B virus (HBV) infection. Herein, we investigated the mechanism of SALL4 re-expression in HBV...

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Udgivet i:Oncogene
Main Authors: Fan, Huitao, Cui, Zhibin, Zhang, Hao, Kailasam Mani, Saravana Kumar, Diab, Ahmed, Lefrancois, Lydie, Fares, Nadim, Merle, Philippe, Andrisani, Ourania
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408304/
https://ncbi.nlm.nih.gov/pubmed/27797380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.399
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