Inhibition of Ectopic Arginine Vasopressin Production by Phenytoin in the Small Cell Lung Cancer Cell Line Lu-165

Phenytoin, a voltage-gated sodium channel (Na(V) channel) antagonist, reportedly inhibits arginine vasopressin (AVP) release from an isolated rat neurohypophysis. So far, it is uncertain whether phenytoin has a direct action on ectopic AVP-producing neuroendocrine tumors. We studied the effect of ph...

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Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Ohta, Takahiro, Mita, Mitsuo, Hishinuma, Shigeru, Ishii-Nozawa, Reiko, Takahashi, Kazuhisa, Shoji, Masaru
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408062/
https://ncbi.nlm.nih.gov/pubmed/28503166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00094
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