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Crystal structure of the essential biotin‐dependent carboxylase AccA3 from Mycobacterium tuberculosis
Biotin‐dependent acetyl‐CoA carboxylases catalyze the committed step in type II fatty acid biosynthesis, the main route for production of membrane phospholipids in bacteria, and are considered a key target for antibacterial drug discovery. Here we describe the first structure of AccA3, an essential...
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| Published in: | FEBS Open Bio |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407890/ https://ncbi.nlm.nih.gov/pubmed/28469974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12212 |
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