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Crystal structure of the essential biotin‐dependent carboxylase AccA3 from Mycobacterium tuberculosis
Biotin‐dependent acetyl‐CoA carboxylases catalyze the committed step in type II fatty acid biosynthesis, the main route for production of membrane phospholipids in bacteria, and are considered a key target for antibacterial drug discovery. Here we describe the first structure of AccA3, an essential...
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| Veröffentlicht in: | FEBS Open Bio |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407890/ https://ncbi.nlm.nih.gov/pubmed/28469974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12212 |
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