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Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain

Bmps regulate numerous neural functions with their regulators. We previously identified Brorin, a neural-specific secreted antagonist of Bmp signaling, in humans, mice, and zebrafish. Mouse Brorin has two cysteine-rich domains containing 10 cysteine residues in its core region, and these are located...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Miyake, Ayumi, Mekata, Yoko, Fujibayashi, Hidenori, Nakanishi, Kazuya, Konishi, Morichika, Itoh, Nobuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407822/
https://ncbi.nlm.nih.gov/pubmed/28448525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176036
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