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Engineering chimeric human and mouse major histocompatibility complex (MHC) class I tetramers for the production of T-cell receptor (TCR) mimic antibodies

Therapeutic monoclonal antibodies targeting cell surface or secreted antigens are among the most effective classes of novel immunotherapies. However, the majority of human proteins and established cancer biomarkers are intracellular. Peptides derived from these intracellular proteins are presented o...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Li, Demin, Bentley, Carol, Yates, Jenna, Salimi, Maryam, Greig, Jenny, Wiblin, Sarah, Hassanali, Tasneem, Banham, Alison H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407768/
https://ncbi.nlm.nih.gov/pubmed/28448627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176642
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