Novel, in-natural-infection subdominant HIV-1 CD8(+) T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines

BACKGROUND: Fine definition of targeted CD8(+) T-cell epitopes and their human leucocyte antigen (HLA) class I restriction informs iterative improvements of HIV-1 T-cell vaccine designs and may predict early vaccine success or failure. Here, lymphocytes from volunteers, who had received candidate HI...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Borthwick, Nicola, Lin, Zhansong, Akahoshi, Tomohiro, Llano, Anuska, Silva-Arrieta, Sandra, Ahmed, Tina, Dorrell, Lucy, Brander, Christian, Murakoshi, Hayato, Takiguchi, Masafumi, Hanke, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407754/
https://ncbi.nlm.nih.gov/pubmed/28448594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176418
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