The impact of anti-drug antibodies on drug concentrations and clinical outcomes in rheumatoid arthritis patients treated with adalimumab, etanercept, or infliximab: Results from a multinational, real-world clinical practice, non-interventional study

OBJECTIVE: To assess the incidence of anti-drug antibodies (ADA) in patients with rheumatoid arthritis (RA) treated with the TNF inhibitors etanercept (ETN), adalimumab (ADL), or infliximab (IFX), and determine the potential relationship with trough drug concentration, efficacy, and patient-reported...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Moots, Robert J., Xavier, Ricardo M., Mok, Chi Chiu, Rahman, Mahboob U., Tsai, Wen-Chan, Al-Maini, Mustafa H., Pavelka, Karel, Mahgoub, Ehab, Kotak, Sameer, Korth-Bradley, Joan, Pedersen, Ron, Mele, Linda, Shen, Qi, Vlahos, Bonnie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407581/
https://ncbi.nlm.nih.gov/pubmed/28448562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175207
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