Heparanase Mediates Intestinal Inflammation and Injury in a Mouse Model of Sepsis

Heparanase, a heparan sulfate (HS)–specific endoglycosidase, plays an important role in inflammation and mediates acute pulmonary and renal injuries during sepsis. To explore its role in septic intestinal injury, a non-anticoagulant heparanase inhibitor, N-desulfated/re-N-acetylated heparin (NAH), w...

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Bibliografiske detaljer
Udgivet i:J Histochem Cytochem
Main Authors: Chen, Song, He, Ying, Hu, Ziwei, Lu, Siyu, Yin, Xiaohan, Ma, Xiaochun, Lv, Chuanzhu, Jin, Guiyun
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407566/
https://ncbi.nlm.nih.gov/pubmed/28170292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155417692536
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