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From chronic immune thrombocytopenia to severe aplastic anemia: recent insights into the evolution of eltrombopag
Thrombopoietin (TPO) is the most potent cytokine stimulating thrombopoiesis. Therapy with exogenous TPO is limited by the formation of antibodies cross-reacting with endogenous TPO. Mimetics of TPO are compounds with no antigenic similarity to TPO. Eltrombopag is an orally-active nonpeptide small mo...
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Publicado no: | Ther Adv Hematol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407506/ https://ncbi.nlm.nih.gov/pubmed/28473904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620717693573 |
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