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From chronic immune thrombocytopenia to severe aplastic anemia: recent insights into the evolution of eltrombopag

Thrombopoietin (TPO) is the most potent cytokine stimulating thrombopoiesis. Therapy with exogenous TPO is limited by the formation of antibodies cross-reacting with endogenous TPO. Mimetics of TPO are compounds with no antigenic similarity to TPO. Eltrombopag is an orally-active nonpeptide small mo...

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Podrobná bibliografie
Vydáno v:Ther Adv Hematol
Hlavní autoři: Gill, Harinder, Wong, Raymond S. M., Kwong, Yok-Lam
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407506/
https://ncbi.nlm.nih.gov/pubmed/28473904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620717693573
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