Endocytic reawakening of motility in jammed epithelia

Dynamics of epithelial monolayers has recently been interpreted in terms of a jamming or rigidity transition. How cells control such phase transitions is, however, unknown. Here we show that RAB5A, a key endocytic protein, is sufficient to induce large-scale, coordinated motility over tens of cells...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Malinverno, Chiara, Corallino, Salvatore, Giavazzi, Fabio, Bergert, Martin, Li, Qingsen, Leoni, Marco, Disanza, Andrea, Frittoli, Emanuela, Oldani, Amanda, Martini, Emanuele, Lendenmann, Tobias, Deflorian, Gianluca, Beznoussenko, Galina V., Poulikakos, Dimos, Haur, ONG Kok, Uroz, Marina, Trepat, Xavier, Parazzoli, Dario, Maiuri, Paolo, Yu, Weimiao, Ferrari, Aldo, Cerbino, Roberto, Scita, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407454/
https://ncbi.nlm.nih.gov/pubmed/28135264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4848
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