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Adenosine receptor-dependent signaling is not obligatory for normobaric and hypobaric hypoxia-induced cerebral vasodilation in humans

Hypoxia increases cerebral blood flow (CBF) with the underlying signaling processes potentially including adenosine. A randomized, double-blinded, and placebo-controlled design, was implemented to determine if adenosine receptor antagonism (theophylline, 3.75 mg/Kg) would reduce the CBF response to...

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Publicat a:J Appl Physiol (1985)
Autors principals: Hoiland, Ryan L., Bain, Anthony R., Tymko, Michael M., Rieger, Mathew G., Howe, Connor A., Willie, Christopher K., Hansen, Alex B., Flück, Daniela, Wildfong, Kevin W., Stembridge, Mike, Subedi, Prajan, Anholm, James, Ainslie, Philip N.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407198/
https://ncbi.nlm.nih.gov/pubmed/28082335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00840.2016
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