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MYC, Cell Competition, and Cell Death in Cancer: The Inseparable Triad

Deregulation of MYC family proteins in cancer is associated with a global reprogramming of gene expression, ultimately promoting glycolytic pathways, cell growth, and proliferation. It is well known that MYC upregulation triggers cell-autonomous apoptosis in normal tissues, while frankly malignant c...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Di Giacomo, Simone, Sollazzo, Manuela, Paglia, Simona, Grifoni, Daniela
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406867/
https://ncbi.nlm.nih.gov/pubmed/28420161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8040120
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