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Modeling and Targeting MYC Genes in Childhood Brain Tumors

Brain tumors are the second most common group of childhood cancers, accounting for about 20%–25% of all pediatric tumors. Deregulated expression of the MYC family of transcription factors, particularly c-MYC and MYCN genes, has been found in many of these neoplasms, and their expression levels are o...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Hutter, Sonja, Bolin, Sara, Weishaupt, Holger, Swartling, Fredrik J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406854/
https://ncbi.nlm.nih.gov/pubmed/28333115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8040107
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