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Search for Modified DNA Sites with the Human Methyl-CpG-Binding Enzyme MBD4
The MBD4 enzyme initiates the process of DNA demethylation by the excision of modified DNA bases, resulting in the formation of apurinic/apyrimidinic sites. MBD4 contains a methyl-CpG-binding domain which provides the localization of the enzyme at the CpG sites, and a DNA glycosylase domain that is...
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| Publicado no: | Acta Naturae |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
A.I. Gordeyev
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406665/ https://ncbi.nlm.nih.gov/pubmed/28461979 |
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