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Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans
Fluoropyrimidines are the first-line treatment for colorectal cancer, but their efficacy is highly variable between patients. We queried whether gut microbes, a known source of inter-individual variability, impacted drug efficacy. Combining two tractable genetic models, the bacterium E. coli and the...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Cell |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Cell Press
2017
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406385/ https://ncbi.nlm.nih.gov/pubmed/28431245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.03.040 |
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