Do Mesenchymal Stem Cells Derived From Atypical Lipomatous Tumors Have Greater Differentiation Potency Than Cells From Normal Adipose Tissues?

BACKGROUND: The p53 protein in mesenchymal stem cells (MSCs) regulates differentiation to osteogenic or adipogenic lineage. Because p53 function is depressed in most malignancies, if MSCs in malignancy also have p53 hypofunction, differentiation therapy to osteogenic or adipogenic lineage may be an...

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Dades bibliogràfiques
Publicat a:Clin Orthop Relat Res
Autors principals: Inatani, Hiroyuki, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Takeuchi, Akihiko, Miwa, Shinji, Higuchi, Takashi, Abe, Kensaku, Taniguchi, Yuta, Yamada, Satoshi, Asai, Kiyofumi, Otsuka, Takanobu, Tsuchiya, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2017
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406341/
https://ncbi.nlm.nih.gov/pubmed/28155209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-017-5259-z
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