Do Mesenchymal Stem Cells Derived From Atypical Lipomatous Tumors Have Greater Differentiation Potency Than Cells From Normal Adipose Tissues?

BACKGROUND: The p53 protein in mesenchymal stem cells (MSCs) regulates differentiation to osteogenic or adipogenic lineage. Because p53 function is depressed in most malignancies, if MSCs in malignancy also have p53 hypofunction, differentiation therapy to osteogenic or adipogenic lineage may be an...

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Detalhes bibliográficos
Publicado no:Clin Orthop Relat Res
Main Authors: Inatani, Hiroyuki, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Takeuchi, Akihiko, Miwa, Shinji, Higuchi, Takashi, Abe, Kensaku, Taniguchi, Yuta, Yamada, Satoshi, Asai, Kiyofumi, Otsuka, Takanobu, Tsuchiya, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406341/
https://ncbi.nlm.nih.gov/pubmed/28155209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-017-5259-z
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