Exposure of adolescent mice to 3,4‐methylenedioxypyrovalerone increases the psychostimulant, rewarding and reinforcing effects of cocaine in adulthood

BACKGROUND AND PURPOSE: 3,4‐Methylenedioxypyrovalerone (MDPV) is a synthetic cathinone with powerful psychostimulant effects. It selectively inhibits the dopamine transporter (DAT) and is 10–50‐fold more potent as a DAT blocker than cocaine, suggesting a high abuse liability. The main objective of t...

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Publicat a:Br J Pharmacol
Autors principals: López‐Arnau, R, Luján, M A, Duart‐Castells, L, Pubill, D, Camarasa, J, Valverde, O, Escubedo, E
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406300/
https://ncbi.nlm.nih.gov/pubmed/28262947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13771
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