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Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models

BACKGROUND AND AIMS: Ductular reaction is a standard component of fibrotic liver tissue but its function is largely unknown. It is supposed to interact with the matrix producing myofibroblasts and compensate the declining regenerative capacity of hepatocytes. The relationship between the extent of f...

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Publicado en:PLoS One
Main Authors: Rókusz, András, Veres, Dániel, Szücs, Armanda, Bugyik, Edina, Mózes, Miklós, Paku, Sándor, Nagy, Péter, Dezső, Katalin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405957/
https://ncbi.nlm.nih.gov/pubmed/28445529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176518
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