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Universal molecular screening does not effectively detect Lynch syndrome in clinical practice
BACKGROUND: Lynch syndrome (LS) due to an inherited damaging mutation in mismatch repair (MMR) genes comprises 3% of all incident colorectal cancer (CRC). Molecular testing using immunohistochemistry (IHC) for MMR proteins is a recommended screening tool to identify LS in incident CRC. This study as...
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| Publicado no: | Therap Adv Gastroenterol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5405883/ https://ncbi.nlm.nih.gov/pubmed/28491141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X17690990 |
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