Syntaxin 11 is required for NK and CD8(+) T-cell cytotoxicity and neutrophil degranulation

Syntaxin 11 (STX11) controls vesicular trafficking and is a key player in exocytosis. Since Stx11 mutations are causally associated with a Familial Hemophagocytic Lymphohistiocytosis (FHL-4), we wanted to clarify whether STX11 is functionally important for key immune cell populations. This was studi...

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Bibliografiska uppgifter
I publikationen:Eur J Immunol
Huvudupphovsmän: D’Orlando, Orietta, Zhao, Fang, Kasper, Brigitte, Orinska, Zane, Müller, Jürgen, Hermans-Borgmeyer, Irm, Griffiths, Gillian M., Zur Stadt, Udo, Bulfone-Paus, Silvia
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405866/
https://ncbi.nlm.nih.gov/pubmed/23042080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142343
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