Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS

OBJECTIVE: To utilize Mendelian randomization to estimate the causal association between low serum vitamin D concentrations, increased body mass index (BMI), and pediatric-onset multiple sclerosis (MS) using genetic risk scores (GRS). METHODS: We constructed an instrumental variable for vitamin D (v...

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Xehetasun bibliografikoak
Argitaratua izan da:Neurology
Egile Nagusiak: Gianfrancesco, Milena A., Stridh, Pernilla, Rhead, Brooke, Shao, Xiaorong, Xu, Edison, Graves, Jennifer S., Chitnis, Tanuja, Waldman, Amy, Lotze, Timothy, Schreiner, Teri, Belman, Anita, Greenberg, Benjamin, Weinstock-Guttman, Bianca, Aaen, Gregory, Tillema, Jan M., Hart, Janace, Caillier, Stacy, Ness, Jayne, Harris, Yolanda, Rubin, Jennifer, Candee, Meghan, Krupp, Lauren, Gorman, Mark, Benson, Leslie, Rodriguez, Moses, Mar, Soe, Kahn, Ilana, Rose, John, Roalstad, Shelly, Casper, T. Charles, Shen, Ling, Quach, Hong, Quach, Diana, Hillert, Jan, Bäärnhielm, Maria, Hedstrom, Anna, Olsson, Tomas, Kockum, Ingrid, Alfredsson, Lars, Metayer, Catherine, Schaefer, Catherine, Barcellos, Lisa F., Waubant, Emmanuelle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2017
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Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405763/
https://ncbi.nlm.nih.gov/pubmed/28356466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003849
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