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Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis

We molecularly dissected leptomeningeal metastasis, or spread of cancer to the cerebrospinal fluid (CSF), a frequent and fatal condition mediated by unknown mechanisms. We selected lung and breast cancer cell lines for the ability to infiltrate and grow in the CSF, a remarkably acellular, mitogen-po...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Boire, Adrienne, Zou, Yilong, Shieh, Jason, Macalinao, Danilo G., Pentsova, Elena, Massagué, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405733/
https://ncbi.nlm.nih.gov/pubmed/28283064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.025
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