Identification of mosaic and segmental aneuploidies by next-generation sequencing in preimplantation genetic screening can improve clinical outcomes compared to array-comparative genomic hybridization

BACKGROUND: Chromosomal mosaicism is observed as the presence of both euploid and aneuploid cells in a particular blastocyst. Recent studies have reported that the implantation rate of mosaic embryo transfer is remarkably lower than the euploid embryos. The superior capability of next-generation seq...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cytogenet
Hauptverfasser: Lai, Hsing-Hua, Chuang, Tzu-Hsuan, Wong, Lin-Kin, Lee, Meng-Ju, Hsieh, Chia-Lin, Wang, Huai-Lin, Chen, Shee-Uan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405548/
https://ncbi.nlm.nih.gov/pubmed/28450889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-017-0315-7
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