Improving preimplantation genetic diagnosis (PGD) reliability by selection of sperm donor with the most informative haplotype

BACKGROUND: The study is aimed to describe a novel strategy that increases the accuracy and reliability of PGD in patients using sperm donation by pre-selecting the donor whose haplotype does not overlap the carrier’s one. METHODS: A panel of 4–9 informative polymorphic markers, flanking the mutatio...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Malcov, Mira, Gold, Veronica, Peleg, Sagit, Frumkin, Tsvia, Azem, Foad, Amit, Ami, Ben-Yosef, Dalit, Yaron, Yuval, Reches, Adi, Barda, Shimi, Kleiman, Sandra E., Yogev, Leah, Hauser, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405512/
https://ncbi.nlm.nih.gov/pubmed/28446182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-017-0247-4
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