Effect of Tetramethylpyrazine on Atherosclerosis and SCAP/SREBP-1c Signaling Pathway in ApoE(−/−) Mice Fed with a High-Fat Diet

Lipid metabolism dysregulation plays a crucial role in the occurrence of atherosclerosis (As). SCAP/SREBP signaling is the main pathway for regulating lipid metabolism. Tetramethylpyrazine (TMP), a Traditional Chinese Medicine (TCM) for treating angina pectoris, has antiatherosclerotic effects and a...

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Vydáno v:Evid Based Complement Alternat Med
Hlavní autoři: Zhang, Ying, Ren, Pan, Kang, Qunfu, Liu, Weihong, Li, Sinai, Li, Ping, Liu, Hongxu, Shang, Juju, Zhang, Lei, Gong, Yanbing, Zhou, Mingxue
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405370/
https://ncbi.nlm.nih.gov/pubmed/28491104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3121989
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