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An optimal stratified Simon two‐stage design

In Phase II oncology trials, therapies are increasingly being evaluated for their effectiveness in specific populations of interest. Such targeted trials require designs that allow for stratification based on the participants' molecular characterisation. A targeted design proposed by Jones and...

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Bibliografiske detaljer
Udgivet i:Pharm Stat
Main Authors: Parashar, Deepak, Bowden, Jack, Starr, Colin, Wernisch, Lorenz, Mander, Adrian
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405342/
https://ncbi.nlm.nih.gov/pubmed/26932771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1742
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