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A cis-eQTL in OPRM1 is Associated with Subjective Response to Alcohol and Alcohol Use

BACKGROUND: A functional polymorphism within the mu-opioid receptor (OPRM1) gene, rs1799971 (A118G), previously has been associated with measures of alcohol use and sensitivity to its effects, but findings have been inconclusive. A recent study suggested that a second nearby variant within OPRM1, rs...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Otto, Jacqueline M., Gizer, Ian R., Deak, Joseph D., Fleming, Kimberly A., Bartholow, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404990/
https://ncbi.nlm.nih.gov/pubmed/28273335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13369
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