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α-Synuclein Promotes Dilation of the Exocytotic Fusion Pore

The protein α-synuclein has a central role in the pathogenesis of Parkinson’s disease (PD). Similar to other proteins that accumulate in neurodegenerative disease, however, the function of α-synuclein remains unknown. Localization to the nerve terminal suggests a role in neurotransmitter release and...

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Pubblicato in:Nat Neurosci
Autori principali: Logan, Todd, Bendor, Jacob, Toupin, Chantal, Thorn, Kurt, Edwards, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404982/
https://ncbi.nlm.nih.gov/pubmed/28288128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4529
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