Dysbiosis of intestinal microbiota and decrease in paneth cell antimicrobial peptide level during acute necrotizing pancreatitis in rats

OBJECTIVES: Intestinal barrier dysfunction plays an important role in acute necrotizing pancreatitis (ANP) and intestinal microbiota dysbiosis was involved in intestinal barrier failure. Paneth cells protect intestinal barrier and are associated with intestinal microbiota. Here, we investigated chan...

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Udgivet i:PLoS One
Main Authors: Chen, Jing, Huang, Chunlan, Wang, Jingjing, Zhou, Hui, Lu, Yingying, Lou, Lihong, Zheng, Junyuan, Tian, Ling, Wang, Xingpeng, Cao, Zhongwei, Zeng, Yue
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404871/
https://ncbi.nlm.nih.gov/pubmed/28441432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176583
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