Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats

BACKGROUND: Emerging evidence reveals that nicotinamide phosphoribosyltransferase (NAMPT) has a significant role in the pathophysiology of the inflammatory process. NAMPT inhibition has a beneficial effect in the treatment of a variety of inflammatory diseases. However, it remains unclear whether NA...

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Bibliografske podrobnosti
izdano v:Respir Res
Main Authors: Wu, Geng-Chin, Liao, Wen-I, Wu, Shu-Yu, Pao, Hsin-Ping, Tang, Shih-En, Li, Min-Hui, Huang, Kun-Lun, Chu, Shi-Jye
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404693/
https://ncbi.nlm.nih.gov/pubmed/28438162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0557-2
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