Recent advances of highly selective CDK4/6 inhibitors in breast cancer

Uncontrolled cell division is the hallmark of cancers. Full understanding of cell cycle regulation would contribute to promising cancer therapies. In particular, cyclin-dependent kinases 4/6 (CDK4/6), which are pivotal drivers of cell proliferation by combination with cyclin D, draw more and more at...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Xu, Hanxiao, Yu, Shengnan, Liu, Qian, Yuan, Xun, Mani, Sridhar, Pestell, Richard G., Wu, Kongming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404666/
https://ncbi.nlm.nih.gov/pubmed/28438180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0467-2
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