Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

BACKGROUND: Chemokine signalling is required for the homing of leukocytes during retinal inflammation, and is associated with pathogenesis of diseases such as age-related macular degeneration (AMD). Here, we explore the role of interleukin-1β (IL-1β) in modulating AMD-associated chemokines Ccl2, Cxc...

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Publicat a:Mol Neurodegener
Autors principals: Natoli, Riccardo, Fernando, Nilisha, Madigan, Michele, Chu-Tan, Joshua A., Valter, Krisztina, Provis, Jan, Rutar, Matt
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404662/
https://ncbi.nlm.nih.gov/pubmed/28438165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0175-y
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