Promising Approaches to Optimize the Biological Properties of the Antimicrobial Peptide Esculentin-1a(1–21)NH(2): Amino Acids Substitution and Conjugation to Nanoparticles

Antimicrobial peptides (AMPs) represent an interesting class of molecules with expanding biological properties which make them a viable alternative for the development of future antibiotic drugs. However, for this purpose, some limitations must be overcome: (i) the poor biostability due to enzymatic...

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Bibliographic Details
Published in:Front Chem
Main Authors: Casciaro, Bruno, Cappiello, Floriana, Cacciafesta, Mauro, Mangoni, Maria Luisa
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404639/
https://ncbi.nlm.nih.gov/pubmed/28487853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00026
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