WCK 5222 (Cefepime-Zidebactam) Antimicrobial Activity against Clinical Isolates of Gram-Negative Bacteria Collected Worldwide in 2015

WCK 5222 consists of cefepime combined with zidebactam, a bicyclo-acyl hydrazide β-lactam enhancer antibiotic with a dual action involving binding to Gram-negative bacterial PBP2 and β-lactamase inhibition. We evaluated the in vitro activity of cefepime-zidebactam against 7,876 contemporary (2015) c...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Sader, Helio S., Castanheira, Mariana, Huband, Michael, Jones, Ronald N., Flamm, Robert K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Epidemiology and Surveillance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404591/
https://ncbi.nlm.nih.gov/pubmed/28242660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00072-17
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