Structural Alteration of OmpR as a Source of Ertapenem Resistance in a CTX-M-15-Producing Escherichia coli O25b:H4 Sequence Type 131 Clinical Isolate

In this study, an ertapenem-nonsusceptible Escherichia coli isolate was investigated to determine the genetic basis for its carbapenem resistance phenotype. This clinical strain was recovered from a patient that received, 1 year previously, ertapenem to treat a cholangitis due to a carbapenem-suscep...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Dupont, Hervé, Choinier, Pascaline, Roche, David, Adiba, Sandine, Sookdeb, Megan, Branger, Catherine, Denamur, Erick, Mammeri, Hedi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404536/
https://ncbi.nlm.nih.gov/pubmed/28264855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00014-17
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