TX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol

OBJECTIVE: To evaluate the pharmacokinetics of TX-004HR vaginal estradiol softgel capsules when used for treating moderate-to-severe dyspareunia in postmenopausal women with vulvar and vaginal atrophy. METHODS: A substudy of the REJOICE trial (multicenter, double-blind, placebo-controlled, phase 3)...

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Publicado en:Menopause
Autores principales: Archer, David F., Constantine, Ginger D., Simon, James A., Kushner, Harvey, Mayer, Philip, Bernick, Brian, Graham, Shelli, Mirkin, Sebastian
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott-Raven Publishers 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404400/
https://ncbi.nlm.nih.gov/pubmed/28002201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0000000000000790
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