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TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in Mice
BACKGROUND & AIMS: Toll-like receptor 4 (TLR4) signaling is activated through 2 adaptor proteins: MyD88 and TIR-domain containing adaptor-inducing interferon-β (TRIF). TLR4 and MyD88 are crucial in nonalcoholic steatohepatitis (NASH) and fibrosis. However, the role of TRIF in TLR4-mediated NASH ...
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| Publicado no: | Cell Mol Gastroenterol Hepatol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403956/ https://ncbi.nlm.nih.gov/pubmed/28462384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.12.004 |
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