TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in Mice

BACKGROUND & AIMS: Toll-like receptor 4 (TLR4) signaling is activated through 2 adaptor proteins: MyD88 and TIR-domain containing adaptor-inducing interferon-β (TRIF). TLR4 and MyD88 are crucial in nonalcoholic steatohepatitis (NASH) and fibrosis. However, the role of TRIF in TLR4-mediated NASH ...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Yang, Ling, Miura, Kouichi, Zhang, Bi, Matsushita, Hiroshi, Yang, Yoon Mee, Liang, Shuang, Song, Jingyi, Roh, Yoon Seok, Seki, Ekihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403956/
https://ncbi.nlm.nih.gov/pubmed/28462384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.12.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi