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Cellular source and proinflammatory roles of high‐mobility group box 1 in surgically injured rat vocal folds
OBJECTIVES/HYPOTHESIS: High‐mobility group box 1 (HMGB1) is a chromatin‐binding protein located in the cell nucleus. Following injury, immunocompetent cells secrete HMGB1 to the extracellular milieu under the stimulation of proinflammatory cytokines. Extracellular HMGB1 acts a danger signal that ins...
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| Udgivet i: | Laryngoscope |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403630/ https://ncbi.nlm.nih.gov/pubmed/27774594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.26333 |
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