Correlation between classic driver oncogene mutations in EGFR, ALK, or ROS1 and 22C3-PD-L1 ≥50% expression in lung adenocarcinoma

INTRODUCTION: Targeted somatic genomic analysis (EGFR, ALK and ROS1) and PD-L1 tumor proportion score (TPS) by immunohistochemistry (IHC) are used for selection of 1(st)-line therapies in advanced lung cancer; however, the frequency of overlap of these biomarkers in routine clinical practice is poor...

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Publicado en:J Thorac Oncol
Autores principales: Rangachari, Deepa, VanderLaan, Paul A., Shea, Meghan, Le, Xiuning, Huberman, Mark S., Kobayashi, Susumu S., Costa, Daniel B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403565/
https://ncbi.nlm.nih.gov/pubmed/28104537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.12.026
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