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Expression and function of MutT homolog 1 in distinct subtypes of breast cancer

Human MutT homolog 1 (MTH1) detoxifies the oxidized DNA precursor 8-oxo-2′-deoxyguanosine-5′-triphosphate and serves a tumor suppressive role in distinct types of cancer. In the present study, the expression of MTH1 was examined in various subtypes of breast cancer, and the effect of its suppression...

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Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: Zhang, Xiaohui, Song, Wei, Zhou, Yidong, Mao, Feng, Lin, Yan, Guan, Jinghong, Sun, Qiang
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403462/
https://ncbi.nlm.nih.gov/pubmed/28454376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5726
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