Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway

This study explored the role of fibulin-4 in osteosarcoma progression and the possible signaling pathway involved. Fibulin-4 mRNA and protein expression in normal tissue, benign fibrous dysplasia, osteosarcoma, osteosarcoma cell lines, the normal osteoblastic cell line hFOB, and different invasive s...

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Bibliografiske detaljer
Udgivet i:Int J Oncol
Main Authors: Zhang, Dong, Wang, Songgang, Chen, Jie, Liu, Haitao, Lu, Jinfa, Jiang, Hua, Huang, Aimin, Chen, Yunzhen
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403358/
https://ncbi.nlm.nih.gov/pubmed/28339091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.3921
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