Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

OBJECTIVES: We tested the hypothesis that oral progesterone administration attenuates drug-induced QT interval lengthening. BACKGROUND: Evidence from preclinical and human investigations suggests that higher serum progesterone concentrations may be protective against drug-induced QT interval lengthe...

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Detalhes bibliográficos
Publicado no:JACC Clin Electrophysiol
Main Authors: Tisdale, James E., Jaynes, Heather A., Overholser, Brian R., Sowinski, Kevin M., Flockhart, David A., Kovacs, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403156/
https://ncbi.nlm.nih.gov/pubmed/28451647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacep.2016.02.015
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