Sustained expression of GLP-1 receptor differentially modulates β-cell functions in diabetic and nondiabetic mice

Glucagon-like peptide 1 (GLP-1) has been shown to play important roles in maintaining β-cell functions, such as insulin secretion and proliferation. While expression levels of GLP-1 receptor (Glp1r) are compromised in the islets of diabetic rodents, it remains unclear when and to what degree Glp1r m...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Kubo, Fumiyo, Miyatsuka, Takeshi, Sasaki, Shugo, Takahara, Mitsuyoshi, Yamamoto, Yuichi, Shimo, Naoki, Watada, Hirotaka, Kaneto, Hideaki, Gannon, Maureen, Matsuoka, Taka-aki, Shimomura, Iichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403141/
https://ncbi.nlm.nih.gov/pubmed/26854076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.01.177
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