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Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

PURPOSE: Prominin-1 (Prom1) is a transmembrane glycoprotein, which is expressed in stem cell lineages, and has recently been implicated in cancer stem cell survival. Mutations in the Prom1 gene have been shown to disrupt photoreceptor disk morphogenesis and cause an autosomal dominant form of Starga...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Bhattacharya, Sujoy, Yin, Jinggang, Winborn, Christina S., Zhang, Qiuhua, Yue, Junming, Chaum, Edward
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403116/
https://ncbi.nlm.nih.gov/pubmed/28437526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21162
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