A gradient of glycolytic activity coordinates FGF and Wnt signaling during elongation of the body axis in amniote embryos

Mammalian embryos transiently exhibit aerobic glycolysis (Warburg effect), a metabolic adaptation also observed in cancer cells. The role of this particular type of metabolism during vertebrate organogenesis is currently unknown. Here, we provide evidence for spatiotemporal regulation of glycolysis...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Oginuma, Masayuki, Moncuquet, Philippe, Xiong, Fengzhu, Karoly, Edward, Chal, Jérome, Guevorkian, Karine, Pourquié, Olivier
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403012/
https://ncbi.nlm.nih.gov/pubmed/28245921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.02.001
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